Hungarian Academy of Sciences, Institute of Enzymology, Biological Research Center, Budapest Hungary
Vrije Universiteit Brussel, Systems Structural Biology
Hij zal onderzoek voeren over “Structural biology of the intrinsically disordered plant chaperone ERD 14” (Structurele biologie van het intrinsiek ontvouwen plant chaperone ERD14).
Zijn Odysseus toelagen (Groep I) bedragen: 2.796.774 EUR, verspreid over 5 jaar. Hij zal in Brussel werken met een team 8 onderzoekers.
o Deputy director, Institute of Enzymology, Hungarian Academy of Sciences (2007-2009)
o Scientific advisor, Institute of Enzymology, Hungarian Academy of Sciences (2006- heden)
o Principal research fellow, Institute of Enzymology, Hungarian Academy of Sciences (1992-heden)
o Research fellow, Institute of Enzymology, Hungarian Academy of Sciences (1986-1992))
o Postgraduate student, Institute of Enzymology, Hungarian Academy of Sciences (1983-1986)
Drie belangrijke publicaties:
Tompa, P. (2003) Intrinsically unstructured proteins evolve by repeat expansion. BioEssays 25: 847- 855
Csizmok, V., Szallosi, E., Friedrich, P. and Tompa, P. (2005) A novel 2D electrophoresis technique for the identification of intrinsically unstructured proteins. Mal. Cell. Proteomics 5: 265-273
Kovacs, 0., Kalmar, E., Torok, Zs. and Tompa, P. (2008) Chaperone activity of ERD10 and ERD14, two disordered stress-related plant proteins. Plant Physiol. 147: 381-390
Uit het jury-rapport:
Peter Tompa is an internationally well established scientist in the field of protein structure and dynamics. He has pioneered the study of intrinsically disordered proteins (together with Keith Dunker). At the moment, he is certainly in a very productive phase of his career. He is well established in the field, has organized international conferences and was invited repeatedly to write reviews in respected journals. The field he has been developing is still in its expansion phase and this implies that his research will be on the forefront in the coming years. In an optimal environment his productivity and impact may increase even further.
Based on groundbreaking developments of the concept of intrinsically unstructured proteins, Dr. Tompa now moves ahead and provides a highly original, well thought-off and highly innovative research plan for the future.
He wishes to study the role of IUPs as chaperones. In particular through application of in-cell NMR experiments, the role of these chaperones will be investigated. This line of this research is no doubt innovative.