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The European Partnership for Personalised Medicine (EP PerMed) – Horizon Europe cofund partnership

This call addresses research studies in personal medicine

Status

“Pharmacogenomic Strategies for Personalised Medicine Approaches (PGxPM2025)”

On the 16th of December 2024 a second joint transnational cofunded call for research projects has been launched within the framework of the Horizon Europe personalised medicine partnership. This partnership will initiate a range of activities the coming years, of which launching calls for research projects form an integral part. The FWO, in its capacity as research funder, will try to engage itself within the research calls of this partnership, in order to support the research institutes from Flanders.

EP PerMed call 2025

The topics of this call are the following:

  • “identification of new pharmacogenomic markers or signatures using (multi)-omics data in relation to drug or drug combination.
  • validation of a pharmacogenomic marker or signatures using (multi)-omics data in predicting  drug or drug combination outcomes.
  • use pharmaco-omics strategies to determine the right dosage, the efficacy of treatments and/or the risk of adverse drug response and non-response to treatment to tailor personalised treatment pathways, including combined treatments (multi-medication).”

Pay attention: projects focussing only on drug-drug-interaction and projects focusing on the clinical development of new drugs are not eligible.

More information

More detailed information on the call scope can be consulted within the call text, which can be found on the relevant EP PerMed webpage.

Al relevant call information can be consulted in this call document, also when it comes to the general rules for participation. In addition, the ‘national/regional’ FWO eligibility criteria have to be respected, which are taken up in the Guidelines for applicants’ document (from p. 21 onwards) and which are of importance when it comes to the eligibility of the subproject from Flanders (FWO).

Submission

Deadline for pre-proposal submission AND national pre-application via the FWO e-loket

18 February 2025, 14.00 CET (Brussels)

FWO-modalities

Both the national/regional FWO fundamental (FO) and Strategic Basic Research (SBO) funding channels are integrated within this multilateral call. The type and scope of the proposed research project will determine the choice of funding channel for the research performed within Flanders (e.g. more fundamental in nature, or more aimed at economical/societal valorisation). Non-compliance with the specific requirements per funding channel might lead to non-eligibility.

Please note, this is only an FWO requirement: European and/or international partners within the project consortium can choose their type of research freely, according to their own national regulations.

For the fundamental funding channel the respective regulations apply. For the SBO channel the SBO regulations have to be taken into account: these imply projects with a primarily economic and/or societal finality, for which ‘valorisation’ is a key - and mandatory - aspect.

Submission

Project proposals have to be submitted by European and international consortia through the ‘EP PerMed’ call secretariat, by making use of the designated pre-proposal template and submission platform, according to the applicable procedures and eligibility criteria included in the call documents and regulations mentioned above.

In case the consortium includes more than one partner requesting funding from FWO, a single online form should be submitted containing all relevant information from the different Flemish partners.

The deadline to submit the administrative application to the FWO is the same as the deadline of the joint transnational call (preproposal stage). To ensure the eligibility of the proposal, it is recommended to consult the FWO administration at least one week in advance.

New: FWO administrative pre-registration

Applicants for FWO funding must submit an administrative application via the FWO e-portal, during the pre-proposal stage only:

  • For fundamental research projects (FO) select the application type: ‘Research projects – European programme fundamental research’.
  • For strategic basis research projects (SBO) select the application type: ‘Research projects – European programme strategic basic research’.

Call budget

The FWO is able to support two projects for a 36 months duration, with an available maximum budget of 350.000 EUR (overhead included) per project/consortium. The FWO budgetary rules, which differ per funding channel, are also clarified in the Guidelines for applicants’ document (from p. 21 onwards).

The cofund partnerships under the Horizon Europe framework programme provide for co-financing by the European Commission in addition to national/regional funds. This can result in additional support at the time of the funding decision, based on the final ranking after international peer review, which can generate additional projects – also for Flanders.

Key points and deviations from the ‘regular’ FWO participatory framework

Some key points and deviations from the ‘regular’ FWO participatory framework to consider:

  • Participation in the framework of the European co-funded partnerships does not interfere with the ‘regular/national’ FWO project submission framework, and is consequently not taken into account with regard to the max. available number of applications that can be applied for/run. However, researchers can only participate in a maximum of two different international consortia per call, provided they concern different subjects.
  • Diverging overhead arrangements apply for what the fundamental and SBO funding channels are concerned, which is clarified in the Guidelines for applicants’ document (from p. 21 onwards).
  • SBO projects aimed at developing a spin-off are not eligible in this context. As such, no mention of this option should be made in the FWO pre-registration document, nor within the EP PerMed proposal.
  • Projects have a max. duration of 36 months and should be budgeted accordingly. Automatic extensions/no-cost prolongations are not accepted in this framework. Consequently, article 28 of the FWO research project regulations and article 14 of the SBO project regulations are explicitly excluded.
  • The PI, for each of the participating institutions from Flanders, must hold an admissible appointment that fully covers the duration of the research project. With regard to the ‘FO’ projects, and more specifically regarding the ‘emeritus’ regulation (artikel 10, §7): it does not apply in this context.
  • In essence the FWO funds pre-clinical research.

Researchers are strongly advised to contact the FWO before submission regarding the eligibility criteria. This to avoid the ineligibility of a researcher individually, and the project consortium as a whole.

Contact

For additional information FWO participation, please contact:

Toon Monbaliu (General and ‘FO’)

europe@fwo.be  

+32 (02)2 550 15 70

Kristien Peeters (‘SBO’)

europe@fwo.be

+32 (0)2 550 15 95